YK11 by Dragon Pharma – Oral Myostatin Inhibitor for Laboratory Research

Muscle-wasting models demand compounds that act through pathways conventional androgens cannot reach, and this is precisely where YK11 attracts investigator attention. Dragon Pharma formulates this steroid-derived small molecule as a 10 mg oral research compound designed to explore myostatin suppression and follistatin upregulation in controlled laboratory settings. Because the mechanism differs from typical SARM activity, screening protocols require careful dose titration and reliable analytical documentation. Consequently, sourcing from a supplier that publishes lot-level test results protects both your budget and your data integrity. Before ordering, review our About Us page to understand how we source, manufacture, and ship every research compound we list.

What Is YK11?

YK11 represents a synthetic steroid-based compound first characterized in 2015 during Japanese university screening programs. Researchers identified it while testing hundreds of molecules for the ability to increase follistatin expression in cultured cells. Follistatin binds and neutralizes myostatin, a primary negative regulator of skeletal muscle growth. Therefore, YK11 functions indirectly: it does not block myostatin itself but rather elevates the body’s natural antagonist against it. Additionally, in vitro studies suggest partial androgen receptor activation at low concentrations, which distinguishes its pharmacological profile from selective androgen receptor modulators. Teams comparing mechanisms often browse additional compounds on our home page before selecting candidates for structure-activity relationship studies.

Composition and Vial Strength

Dragon Pharma supplies YK11 as pharmaceutical-grade powder pressed into 10 mg oral tablets or provided as bulk crystalline material, depending on the requested format. Each unit states the exact active-mass content so technicians calculate dosing without ambiguity. In addition, every production lot undergoes HPLC purity assessment and mass spectrometry confirmation before release. We recommend requesting the certificate of analysis (CoA) tied to your specific lot number before protocol development begins. If you want help interpreting these documents, our FAQ section answers the most common questions from first-time and repeat buyers alike.

Research Applications and Study Models

Laboratories use YK11 primarily in cell-culture experiments examining satellite cell proliferation and differentiation pathways. Furthermore, animal models of sarcopenia and cachexia benefit from comparative studies measuring follistatin mRNA levels after oral administration. Some groups also test the compound alongside conventional myostatin antibodies to evaluate additive effects. Because bioavailability data remain limited, investigators frequently run parallel pharmacokinetic sampling to characterize absorption windows. These applications make YK11 a useful probe for understanding upstream regulators within the TGF-beta signaling cascade rather than a finished therapeutic candidate.

Dosing Considerations for Protocol Designers

Please note that the labelled amount never functions as an administration instruction; instead, qualified personnel develop dosing schedules based on species, route, and experimental endpoint. Published literature reports effective concentrations ranging widely between in vitro assays and whole-animal studies. Therefore, pilot runs with narrow dose ranges help establish working parameters before committing larger cohorts. Moreover, record each calculation step in your lab notebook so colleagues can reproduce results exactly under identical conditions.

Verifying Authenticity Before You Run Your Study

Counterfeit research compounds damage experiments and waste funding. Therefore, verification should rank among your very first actions upon delivery. Every Dragon Pharma product carries security features that you can cross-check against our database in seconds. Simply enter your lot details on the Product Verification page, and the system confirms whether your unit matches a genuine production run. Additionally, compare printed CoA values against internal QC thresholds. Should any discrepancy appear, contact us immediately rather than proceeding with the study.

Storage, Shipping, and Handling

Unopened units stay stable at room temperature, away from direct light and moisture. During transit, we dispatch orders in protective packaging that shields tablets or powder from crushing and humidity exposure. Usually, processing completes within one business day, and tracking information follows by email. However, regulations differ between regions; consequently, review your local import rules for investigational compounds before checkout. Transparency here prevents delays and keeps your project moving on schedule.

Important Research-Use Statement

This product serves strictly laboratory and preclinical investigation. It is not an FDA-approved medicine, and it does not intend human or veterinary use. Furthermore, it remains unapproved for athletic or performance purposes anywhere in the world. Qualified personnel should handle all procedures under appropriate institutional protocols and safety equipment.

Order With Confidence

Your procurement team deserves a partner combining traceable sourcing, responsive support, and rigorous documentation. To place an order, request pricing, or ask protocol-support questions about YK11, reach our specialists through the Contact page, and we will reply promptly with stock availability and lot information. Launch your next muscle-biology study with material you can trust.